Quinazoline, 4,7-dichloro-6-Methoxy- - Names and Identifiers
Quinazoline, 4,7-dichloro-6-Methoxy- - Physico-chemical Properties
Molecular Formula | C9H6Cl2N2O
|
Molar Mass | 229.06 |
Density | 1.450±0.06 g/cm3(Predicted) |
Boling Point | 354.2±37.0 °C(Predicted) |
pKa | -0.12±0.30(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Quinazoline, 4,7-dichloro-6-Methoxy- - Introduction
4, the chemical formula is C9H6Cl2N2O, is an organic compound. Its properties are as follows:
1. Appearance: 4. It is a white to light yellow solid.
2. Solubility: It has good solubility in organic solvents, such as dimethyl sulfoxide and dichloromethane, but has low solubility in water.
3. Melting point: Its melting point is between 132-134 degrees Celsius.
4. Stability: 4. It can be stored stably under dry, dark and sealed conditions.
4, the use of Lin mainly includes the field of medicine and agriculture:
1. Pharmaceutical field: The compound is widely used in the synthesis of anti-cancer drugs, and has potential anti-tumor activity.
2. Agricultural field: 4. It is an important precursor of fungicides and herbicides, which can be used to prepare new pesticides.
Preparation 4, the method can be carried out by the following steps:
1. first with 2,5-dichloro -3,4-dimethoxy quinazoline as raw material, under alkaline conditions with known chlorinated alkylation agent reaction.
2. Substitute the alcohol group during the reaction to get 4.
Regarding the safety information of this compound, the following points should be noted:
1. Avoid contact with eyes and skin. If contact occurs, rinse immediately with plenty of water and seek medical help.
2. Wear appropriate protective equipment such as lab gloves, goggles and protective clothing when using or handling the compound.
3. When using or storing 4. Keep away from fire and heat sources to prevent them from burning and exploding.
4. It should be operated in a well-ventilated area and avoid inhaling the gas or dust of the compound.
When handling this compound, it is recommended to operate in accordance with the safe operating procedures and guidelines of the area where it is located, and strictly abide by relevant safety practices.
Last Update:2024-04-09 21:54:55